The following study analyzes responses concerning gender-based and sexual harassment from the Women Physicians’ Health Study, a nationally distributed questionnaire study (4501 respondents). Overall, 47.7% of women physicians reported ever experiencing gender-based harassment, and 36.9% reported sexual harassment. Harassment was more common while in medical school or during internship, residency, or fellowship than in practice. Those who felt in control of their work environments, were satisfied with their careers, and would choose again to become physicians reported lower prevalences of ever experiencing harassment. Those with histories of depression or suicide attempts were more likely to report ever having been harassed.