Action Collaborative on Translating Emerging Science, Technology, and Innovation in Health and Medicine
Breakthroughs in biomedical research, data science, and technology are revolutionizing health and medicine—unlocking immense potential while challenging the scientific community to navigate critical challenges related to access, cost, ethics, and broader societal impacts.

About the Program
The Action Collaborative on Translating Emerging Science, Technology, and Innovation (ACT-ESTI) is a public-private partnership dedicated to advancing a responsible biomedical innovation ecosystem. Through collective action across sectors, ACT-ESTI members work to ensure that scientific and technological advances in health and medicine are responsive to individual and societal needs while helping society anticipate and address their broader implications.
Taking a systems-level approach, ACT-ESTI focuses on two key workstreams: fostering a culture of responsible innovation and strengthening anticipatory governance. The first workstream explores how stakeholders—researchers, funders, publishers, investors, and regulators—can integrate ethical and societal considerations into the innovation process, aligning incentives and governance frameworks to promote responsible research and development. The second workstream pilots tools to assess emerging technologies before commercialization, ensuring they align with ethical, economic, and societal priorities. Together, these efforts aim to create structured, scalable approaches that guide responsible biomedical innovation.
Proceedings
In May 2024, the National Academy of Medicine convened experts to examine the unintended consequences of biomedical advancements and the importance of ethical innovation. The workshop proceedings lay the groundwork for a future where innovation in health and medicine is not only groundbreaking but ensures scientific progress serves society responsibly.
Case Studies


Featured
Toward Equitable Innovation in Health and Medicine
The National Academies, in partnership with the National Academy of Medicine, appointed an expert committee tasked with developing a governance framework that aligns transformative health and medical innovations with ethical and equitable principles. The resulting report outlines strategies to ensure innovation is more inclusive, responsive, and capable of addressing inequities throughout its life cycle.
Additional Resources
Program Team
Staff




Sponsors
Contact Information
Questions?
Please contact us at [email protected]. You can also join our mailing list for program updates.