This study, published in the Journal of General Internal Medicine, determines whether a longitudinal stress management and resilience course improves well-being among first-year medical students. The findings show that mental quality of life, happiness, and cognitive and emotive empathy declined and stress scores increased over the course of the year. No statistically significant differences in burnout or resilience were seen. Overall, the required course did not lead to measurable improvements in first-year medical student well-being or empathy, contrasting findings from interventional studies using volunteer medical students or physicians. The study advises offering a variety of effective options so that students can select activities they want to engage in.