The following study evaluates the prevalence of and risk factors for psychiatric symptoms and disorders and for personal health behaviors among among clinicians at an academic medical center. The prevalence of current depressive symptoms was 29%; prevalence of high likelihood of harmful alcohol consumption, 6%; the use of sedatives or hypnotics without a prescription in the past 12 months, 5%. The characteristics associated with depressive symptoms were living alone, full time salaried faculty status, not having a primary care physician, female sex, and age < 50 years and risk factors were male sex, house staff status, and not being exclusively heterosexual. The research advises engaging physicians in primary care relationships and social support for those at risk for depression, suicide, and substance abuse.