This book explores the important topic of mental health and related problems among physicians and trainees. Separated into three parts with overlapping themes, the book is for care providers, leaders, and organizations. Part I focuses on symptoms and manifestation of problems at the workplace, part II on disorders underlying the symptoms, and part III on individual and organizational interventions. The continuum of health and well-being is investigated with developmental context. All in all, the authors wrote the book to outline effective pathways to well-being and a healthy work-life balance, to foster optimal and safe patient-care.