On-call work has been associated with medical errors, injuries and lower clinician well-being. This study, published in Occupational Medicine, examines whether working on-call would predict psychological distress, job satisfaction and possible mechanisms through which the association is mediated. Overall, the results found that sleeping problems and work interference with family act as mechanisms in the association of on-call duties with high distress, low job satisfaction and low work ability. The research advises interventions enabling physicians to connect work and family and promoting protected sleep time and better sleep.