This article, published in JAMA Network, highlights and defines job dissatisfaction and burnout of all specialties in the context of early childhood development, work stressors, personality factors, and female experience. All are framed as individual factors; both individual and organizational responsibilities, roles, and, strategies are developed from cited peer-reviewed research articles. Physicians must be guided throughout training and practice to cultivate methods of personal renewal, emotional self-awareness, connection with social support systems, and a sense of mastery and meaning in their work.