This qualitative survey study, published in BMC Family Practice, reports factors hindering and promoting well-being among physicians. Four major themes emerged from survey responses: (1) external constraints on the practice of medicine, (2) issues at the professional/institutional levels, (3) issues at the individual practice level, and (4) work/life balance. Factors hindering (work-life conflict, lack of resources, and restrictions to autonomy) and factors promoting (health promotion and healthy workplace initiatives, collegiality/professionalism, and policy formulation) well-being have large-scale implications for governance, human resources, and education, supporting use of socio-ecological framework to analyse physician well-being.