The following systematic review examines the costs of team-based care for blood pressure control. 31 studies published between 1980 and 2012 were analyzed for intervention cost, healthcare cost averted, benefit-to-cost ratios, and cost-effectiveness. The quality of estimates for intervention and healthcare cost from each study were assessed on intervention focus on blood pressure control, incremental estimates in the intervention group relative to a control group, and inclusion of major cost-driving elements in estimates. Results show that team-based care to improve blood pressure control is cost-effective.