The following study assesses the impact of weekend respite, with consequent reduction in continuity of care, for intensive care unit physicians and their patients. The primary outcome was ICU length of stay and physician burnout and secondary outcomes were hospital LOS and mortality rates. The results find that interrupted scheduling with weekend respite resulted in non-significant increases in LOS and mortality. Intensivists experienced significantly higher burnout, work–home life imbalance, and job distress working under the continuous schedule compared with intensivists working under interrupted scheduling (with weekend respite).