The following study assesses the prevalence and causes of burnout in rural physician assistants by using the Maslach Burnout Inventory. Findings show that respondents were measured to have high to moderate emtional exhuastion and depersonalization subscores and a low to moderate personal accomplishment subscore. To begin addressing burnout within these communities, the authors suggest adjusting rural physician assistant workload and support, enhancing professional communications, and addressing burnout prevention techniques within physician assistant training programs.