The alarming increase in physician burnout and stress is is true not only for physicians on the front lines of medical care but also for specialists in medical oncology. Physician burnout not only is an issue for the medical profession but also has been increasingly linked to the delivery of quality care and national workforce needs. Satisfaction with work-life balance and burnout were the strongest predictors of intent to reduce clinical work hours and leave one’s current position. Clearly, these findings have significant implication on the future of healthcare.