This study, published in the Journal of Continuing Education in the Health Professions, aimed to test the acceptability and effectiveness of a two-phase mindfulness-based stress reduction program (8-week initial treatment plus a 10-month maintenance phase) in alleviating work stress-related symptoms (i.e., burnout, heart rate [HR], and blood pressure [BP]) in a sample of 42 physicians. Researchers utilized a randomized controlled trial and a simple pre-post design, respectively, for each of the two phases of the study. After the initial 8 weeks of treatment, significant improvements for the experimental group in mindfulness levels and reductions in emotional exhaustion, HR, and BP were obtained, and effect sizes significantly increased over the 10-month maintenance period. Results suggest that a mindfulness-based stress reduction program has practical consequences for reducing and controlling risks of developing burnout and cardiovascular disease in this population and enhancing well-being in life.