In this study, a cross-sectional survey and subsequent analysis measures resilience, burnout, compassion satisfaction, personal meaning in patient care and intolerance of uncertainty in Australian general practice (GP) registrars (equivalent of specialty fellows in the US). Fourteen percent of registrars were found to be at risk for burnout using the single-item scale, but none using the ProQOL scale. Associated risk factors are secondary traumatic stress, general intolerance of uncertainty, anxiety due to clinical uncertainty and reluctance to disclose uncertainty to patients. Only 10% have high resilience scores. Resilience is positively associated with compassion satisfaction and personal meaning in patient care. Registrars are generally determined to have lower burnout and higher resilience.