The following systematic review evaluates the effectiveness of CDSS in improving quality of type II diabetes care. It also highlights the key indicators of quality improvement to assist policy makers in development of future diabetes care policies through the integration of information technology and system. Results show that a significant improvement has been found in the process of care for all three measures of quality of diabetes care. However, weak to modest positive results are observed for the clinical measures of the diabetes care indicators. In addition to this, technology adoption of CDSS is found to be consistently low.