Imagine that every time you see a doctor, visit the hospital, or speak with your insurance company, those interactions help improve not only the U.S. health systems’ overall performance but, most importantly, your health outcomes. That vision for a Learning Health System (LHS) is within reach, and with technologies like artificial intelligence and increasing demand for modern and affordable health care, it is closer than ever. By collaborating and aligning the stakeholders across the health ecosystem—from doctors and device manufacturers to insurers and policymakers to patients and families—the health ecosystem can fulfill expectations for continuous sustained improvements for all.

Extraordinary advances in digital health capacity, new research approaches, and a growing appreciation for the need to more rapidly adopt lessons learned about effective interventions offer the nation both an opportunity and pressing imperative to implement the Shared Commitments of the LHS as a means of providing common ground for systematic, sustained, and focused improvements.

Shared Commitments: A Trust Framework

Health and health care that is…

ENGAGED

Gives primacy to understanding, caring, and acting on people’s goals

SAFE

Deploys verified protocols to safeguard against risk from unintended harm

EFFECTIVE

Applies continuously updated evidence to target goal achievement

EQUITABLE

Advances parity in individual opportunity to reach full health potential

EFFICIENT

Delivers optimal outcomes and affordability for accessible resources

ACCESSIBLE

Provides timely, convenient, interoperable, and affordable services

ACCOUNTABLE

Identifies clear responsibilities, measures that matter, and reliable feedback

TRANSPARENT

Displays full clarity and sharing in activities, processes, results, and reports

SECURE

Embeds safeguards in access, sharing and use of data and digital/AI tools

ADAPTIVE

Centers continuous learning and improvement in organizational practices

A Trust Framework for the Common Good​​

Shared Commitments Initiative

The National Academy of Medicine seeks to accelerate transformation of health and health care outcomes to improve quality, safety, patient-centeredness, and affordability through the LHS Shared Commitments Initiative.

The Shared Commitments Initiative is a multi-phased, multi-year project to facilitate widespread adoption of the pillars, operational features, and Shared Commitments of an LHS by engaging with a broad range of health sectors, disciplines, and stakeholders in a collaborative movement. The Shared Commitments were developed using nearly two decades of consensus reports—including To Err is Human, Crossing the Quality Chasm, and Best Care at Lower Cost—workshops, and committees, and offer a trust framework for health and health care, representing the expectations and commitments for health systems on behalf of all health stewards. Implementation is guided by a Strategy Group comprising individuals from leading organizations from across the health ecosystem.

Strategy Group Co-Chairs

Executive Director
Patient-Centered Outcomes Research Institute (PCORI)
Nakela Cook is the executive director at the Patient-Centered Outcomes Research Institute (PCORI). She is a cardiologist and health services researcher with a distinguished career leading key scientific initiatives engaging patients, clinicians, and other health care stakeholders at some of the nation’s largest health research funders. Cook leads PCORI’s research, engagement, dissemination and implementation, and research infrastructure development work. She also provides oversight to a growing number of programs and initiatives designed to create a more efficient, effective, and patient-centered system of health. Under her leadership, and with extensive engagement of stakeholders, PCORI established a bold strategic vision to address the challenges that patients and communities face in our nation’s complex, fast-changing health system. Prior to her current role, Cook served as senior scientific officer and chief of staff at the National Heart, Lung, and Blood Institute where she spearheaded initiatives in strategic planning, cardiovascular outcomes, precision medicine, data science, sickle cell disease, and women’s health. Cook has received numerous awards for her excellence in clinical teaching, mentorship, and leadership of complex scientific initiatives and was named as one of Modern Healthcare’s 100 Most Influential People for 2023 and 2024. Cook earned her medical degree from Harvard Medical School and a Master of Public Health in health care policy and management from Harvard School of Public Health. She completed her clinical training at Massachusetts General Hospital in Boston and is an alumna of the Commonwealth Fund/Harvard University Fellowship in Minority Health Policy.
Chief Value Officer; Associate Dean for Practice Transformation; Professor, Gynecologic Oncology
Mayo Clinic

Sean Dowdy is the Chief Value Officer at Mayo Clinic. Dr. Dowdy earned his bachelor’s degree in English at Cornell University and attended Georgetown University School of Medicine where he earned his medical degree. He completed residency in obstetrics and gynecology in addition to a fellowship in gynecologic oncology at Mayo Clinic School of Graduate Medical Education. He completed postgraduate clinical training in Lille, France, and Berlin, Germany, in laparoscopic surgical oncology. In his role as Chief Value Officer of Mayo Clinic and the Robert D. and Patricia E. Kern Associate Dean for Practice Transformation, Dr. Dowdy leads the strategy and execution for Mayo Clinic Quality and Affordability and for Mayo Clinic’s learning health system. In these roles he fortifies Mayo Clinic’s brand and reputation as a category of one within health care as aligned with Mayo Clinic’s Bold. Forward. 2030 Strategy. His current research focuses on improving healthcare quality, safety, and value, and he has worked to disseminate his surgical quality improvements beyond Mayo Clinic to national and international audiences. Dr. Dowdy is credited with approximately 300 peer-reviewed publications. He serves as an associate editor of the journal, Gynecologic Oncology, and has held multiple leadership positions in international societies including serving as a member of the Board of Directors for the Society of Gynecologic Oncology, ERAS USA, and Society of Gynecologic Surgeons.

Cincinnati Children’s Professor of Pediatrics at the James M. Anderson Center for Health System Excellence
Cincinnati Children’s Hospital Medical Center

Peter Margolis is the Cincinnati Children’s Professor of Pediatrics at the James M. Anderson Center for Health System Excellence at Cincinnati Children’s Hospital Medical Center. His work encompasses the application and study of systems improvement methods across a broad range of areas, including primary and sub‐specialty care, communities, and public health settings to improve the health outcomes of children, families, and communities. He served as Co‐Director of the Center from 2016‐2024 and currently leads the Center’s efforts focused on advancing the science of networked Learning Health Systems. Over the last 20 years, he and his research team have developed innovative approaches that engage patients, their families, clinicians, scientists, and communities in developing network‐based learning health systems that simultaneously improve care, spawn innovation, and accelerate research. This work has repeatedly demonstrated significant impact on the process and outcomes of care. Dr. Margolis was co‐ PI of an NIH Transformative Research Grant focused on developing learning health systems for children with chronic illness by harnessing the inherent motivation and expertise of all stakeholders involved. Dr. Margolis has extensive experience in large‐scale comparative effectiveness research, the creation of large‐scale interoperable data systems, managing large project teams, and engaging individuals from diverse backgrounds to co‐produce improved care and research. He served as Chair of the PCORnet Council, guiding the Patient‐Centered Outcomes Research Institute’s investment in transforming research infrastructure in the US. The ImproveCareNow Network, which he leads, was awarded the Drucker Prize, the largest on‐profit management and innovation award in the US. Dr. Margolis is an elected member of the National Academy of Medicine.

Working Groups

The collaborative Strategy Group of health leaders shape the initiative’s overall direction and inform activities of cooperative working groups to address gaps and priorities for spreading and scaling the Shared Commitments. Current working groups focus on communication and messaging, operational requirements, and strategies for infrastructure investment.

Communication and Messaging

  • Describing the shared benefits of the learning health system in plain language informed by stakeholder priorities, responsibilities, and values needed to advance progress
  • Demonstrating what the Shared Commitments look like in practice, including how the LHS approach can help improve health system performance and achieve people’s health goals.

Operational Requirements

  • Showing how the Shared Commitments bolster and reinforce existing goals and frameworks for health care quality and improvement.
  • Providing insights for understanding and evaluating progress toward the anchor features of the LHS in various real-world settings and sectors.

Infrastructure Investment Strategies

  • Identifying sustainable financial models and aligned incentive structures to advance the LHS.
  • Demonstrating a business model and strategies that highlight the financial benefits and return on investment made possible by the LHS approach.