Biomedical Science and Research
by Jenna Ogilvie | Dec 17, 2018 | Discussion Paper, Perspectives
Introduction Breast cancer is the most common malignancy among women in the United States, with over 260,000 new cases and over 40,000 deaths estimated to occur in 2018 [1]. Although most breast cancers are diagnosed with disease localized to the breast or breast... 
by Jenna Ogilvie | Dec 10, 2018 | Commentary, Perspectives
Heterogeneous responses to the same therapy among individual patients are commonplace in both biomedical research and patient care. Despite being considered by many as the pinnacle of the evidence-based medicine hierarchy, parallel group randomized clinical trials... 
by Jenna Ogilvie | Dec 3, 2018 | Discussion Paper, Perspectives
The central idea of early disease detection and treatment is essentially simple. However, the path to its successful achievement (on the one hand, bringing to treatment those with previously undetected disease, and, on the other, avoiding harm to those persons not... 
by Jenna Ogilvie | Nov 19, 2018 | Commentary, Perspectives
Introduction On January 14, 2015, the Institute of Medicine (IOM) released a consensus study report titled Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk [1], which detailed guiding principles and a practical framework for responsibly managing... 
by Jenna Ogilvie | Oct 22, 2018 | Commentary, Perspectives
Controlling or reducing the risk for cancer was a principal goal of the National Cancer Act, signed by President Nixon in 1971. Long before the human genome was sequenced, and the etiology of many cancers was understood, Americans were determined to find a way to... Page 1 of 1212345...10...»Last » 