Workshop discussions will explore accelerating the use of large simple trials (LSTs) to improve the speed and practicality of knowledge generation for medical decision making and medical product development; the concepts of LST design, examples of successful LSTs, the relative advantages of LSTs, and the infrastructure needed to build LST capacity as a routine function of care; the structural, cultural, and regulatory barriers hindering the development of an enhanced LST capacity; and the needs and strategies in building public demand for, and participation in LSTs. Participants also will consider near-tearm strategies for accelerating progress in the uptake of LSTs in the United States.
This workshop is co-sponsored with the IOM Forum on Drug Discovery, Development, and Translation.
