Engineering Better Medicine for Public Health Crises and the Future

By Roderic I. Pettigrew
July 27, 2020 | Commentary

 

When my brother told me he had been diagnosed with COVID-19, I was scared. My memory immediately jumped to visions of his childhood struggles with asthma, which he described as having an ever-tightening chain around his chest. I thought of intubated COVID-19 patients at so many hospitals across the nation, and all of the patients who did not leave the hospitals alive. As we now know, African-American men like my brother are several times more likely to die from COVID-19 than someone who is white [1].

In my home state of Georgia, for example, 80 percent of all patients hospitalized due to COVID-19 in March 2020 were Black people. Nationally through June, American Indians, Native Alaskans, and Black people have had a hospitalization rate that is five times more than whites. For Hispanic people it is four times higher [2]. The compounding factors of increased rates of comorbidities, reduced access to care, limited resources inclusive of health guidance information, and even trust in mainstream medicine no doubt make these populations more vulnerable to a raging viral illness.

Thus, this pandemic has dramatically revealed a deeply rooted national challenge in delivering equitable health care for all Americans. Indeed, while our nation fights the pandemic, it must simultaneously work on addressing systemic inequities and the social marginalization of minority communities that is making the pandemic worse for everyone.

The battle with COVID-19 is on several fronts, involving not just the novel virus but also inadequacies in the nation’s medical system, the disproportionate impact on communities of color, and the devastated economy and educational institutions. All of these are intertwined. To prevail, our nation needs to follow the science that leads to practical solutions. The advice and guidance of seasoned medical and public health professionals are obviously essential. But another, perhaps less obvious, group that is key to tackling these complex challenges is engineers.

In your unconscious mind, you know that already. The modern world is built by and runs on the ingenuity of engineers—from the systems that meet modern energy needs to your smartphone to, well, your whole way of life.

The engineering “to-do” list to combat COVID-19 and assist in safely opening society is long. It includes the expedited design and distribution of rapid point-of-care and at-home diagnostic tests, predictive analytics that indicate infection before symptoms are evident, efficient contact tracing systems, effective anti-viral and immunomodulatory drugs, and highly eff active vaccines with simple – even self-administered – delivery systems. Engineers are critical to further enhance telemedicine functionality for the long term, develop communication systems for personalized health prompts and connections to local services, create predictive models of disease spread, and determine the effectiveness of emerging efforts against the virus.

This work will help keep all of us and our economy healthy. If designed with purposeful intention, it could also provide approaches to help redress socially-based inequities. But we must keep social issues at the forefront of our minds. The history of biotechnology development has been fraught with a lack of diversity in technical teams, contributing to the creation of algorithms and products that increase and exacerbate racial and gender disparities rather than solve them. Technological innovations have often been made inaccessible to underserved populations due to cost, practice norms, and technical barriers [3]. Solutions that benefit only the wealthy, a given racial group, or those with high health literacy do not help all of us. Responsive innovations should be designed with accessibility, ease of use, and social application in mind. They should also be engineered to help infuse greater cultural humility among health care providers, thus facilitating better outcomes for those with demonstrably greater needs. For example, a simple automated procedure checklist tailored for each situation might help standardize approaches and equilibrate the quality of the outcomes [4].

I envision a deeper integration of clinicians and engineers to meet these challenges. More specifically, the potent strategies that are native to engineering are profoundly relevant to our goals of achieving health care equity. And better outcomes across all zip codes, would be a significant step to a better world. Engineers can design to boundary conditions to ensure that clinical solutions are effective, inclusive, and widely available. The nation’s diverse audiences should be targeted in the design process to further enhance applicability and utility across demographics. Newly fashioned solutions could come from a convergence of skills in engineering, medicine and the social sciences to go beyond current levels of effectiveness.

As the engineering community has done in so many other critical moments in history, it can step in as practical problem solvers to help meet pandemic and derivative challenges. For example, the NIH’s recent RADx initiative encourages the medical and engineering communities to develop innovative technologies for COVID-19 testing in high volumes [5]. And the National Academy of Engineering has launched a multi-generational, multi-disciplinary COVID-19 Call for Engineering Action [6] that notes “COVID-19 separates us physically”, but “also compels us to work together.” Indeed, we need young dreamers and seasoned experts alike to brainstorm and implement creative solutions to this unprecedented crisis and those to come. The need for clinicians and engineers to blend their expertise and create integrated solutions that benefit everyone has never been more demonstrably evident.

Our rush to respond to a particularly thorny virus comes amid a period of remarkable global social awareness that has made long-standing social inequities more apparent. We now have an opportunity to take on the interwoven roots of racial and ethnic disparities that have allowed the pandemic to take hold so strongly among our most neglected communities.

This confluence of challenges compels us to support and encourage a new generation that blends the skills of physicians and engineers—“physicianeers”—to create real change-makers. The COVID-19 Call for Engineering Action is a great start with expansive potential through the convergence of these disciplines. Perhaps a transformative development from such integrated expertise in this innovation incubator will immediately help save lives in our current crisis. But it could also inspire an emerging talent to pursue a career that merges engineering, medicine, and related disciplines to make our global community healthier, more equitable and more harmonious in ways that we cannot yet even imagine.

 


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Tweet this!  Engineers and health professionals must work together to address the complicated challenges ahead, including #COVID19. A new #NAMPerspectives calls for continued collaboration: https://doi.org/10.31478/202007c

Tweet this!  “Solutions that benefit only the wealthy, a given racial group, or those with high health literacy do not help all of us.” A new #NAMPerspectives commentary calls engineers and clinicians to join forces to combat complex challenges like #COVID19: https://doi.org/10.31478/202007c

Tweet this!  @theNAEng’s COVID-19 Call for Engineering Action notes that #COVID19 separates us physically but compels us to work together. A new #NAMPerspectives deepens that sentiment, with a call for engineers and health professionals to work together: https://doi.org/10.31478/202007c

 

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References

  1. Hathaway, B. 2020. New analysis quantifies risk of COVID-19 to racial, ethnic minorities. YaleNews. Available at: https://news.yale.edu/2020/05/19/new-analysis-quantifies-risk-covid-19-racial-ethnic-minorities (accessed July 9, 2020).
  2. Centers for Disease Control and Prevention. 2020. COVID-19 in Racial and Ethnic Minority Groups. Available at: https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/racial-ethnic-minorities.html (accessed July 7, 2020).
  3. Matheny, M., S. Thadaney Israni, M. Ahmed, and D. Whicher, Editors. 2019. Artificial Intelligence in Health Care: The Hope, the Hype, the Promise, the Peril. NAM Special Publication. Washington, DC: National Academy of Medicine. Available at: https://nam.edu/wp-content/uploads/2019/12/AI-in-Health-Care-PREPUB-FINAL.pdf (accessed July 7, 2020).
  4. Gawande, A. 2009. The Checklist Manifesto: How to Get Things Right. New York: Metropolitan Books, Henry Holt and Company.
  5. NIH Rapid Acceleration of Diagnostics (RADx) Program. 2020. Available at: https://www.nih.gov/research-training/medical-research-initiatives/radx (accessed July 27, 2020).
  6. National Academy of Engineering. 2020. National Academy of Engineering COVID-19 Call for Engineering Action. Available at: https://www.nae.edu/230195/Call-for-Engineering-Response-to-the-COVID19-Crisis (accessed July 7, 2020).

DOI

https://doi.org/10.31478/202007c

Suggested Citation

Pettigrew, R. I. 2020. Engineering Better Medicine for Public Health Crises and the Future. NAM Perspectives. Commentary, National Academy of Medicine, Washington, DC. https://doi.org/10.3147/202007c

Author Information

Roderic I. Pettigrew, PhD, MD, is the chief executive officer of Engineering Health (EnHealth) and executive dean for Engineering Medicine (EnMed) at Texas A&M University and Houston Methodist Hospital, and was the founding director of the National Institute of Biomedical Imaging and Bioengineering at the National Institutes of Health. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the American Academy of Arts & Sciences.

Acknowledgments

This commentary benefitted from multiple discussions with Randy Atkins, previously Director of Communications and Media Relations for the National Academy of Engineering, and Richard Ehman, MD, the Blanche & Richard Erlanger Professor of Medical Research, Mayo Clinic and member of the National Academy of Medicine.

Conflict-of-Interest Disclosures

Dr. Pettigrew reports having three patents pending: for a method and system of sterilization of medical garments, a reusable N95 mask, and an ENT isolation helmet.

Correspondence

Questions or comments should be directed to Roderic Pettigrew at pettigrew@tamu.edu.

Disclaimer

The views expressed in this paper are those of the authors and not necessarily of the authors’ organizations, the National Academy of Medicine (NAM), or the National Academies of Sciences, Engineering, and Medicine (the National Academies). The paper is intended to help inform and stimulate discussion. It is not a report of the NAM or the National Academies. Copyright by the National Academy of Sciences. All rights reserved.


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