National Academy of Medicine

Novel Ways to Get Good Trial Data: The UK Experience

Traditional randomized clinical trials are very expensive and time-consuming and often have poor external validity (Ware and Hamel,
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Health Research as a Public Good

The arrangements for the regulation and governance of health research in the United Kingdom (UK) have evolved, piecemeal, over the past 30 years, and m
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Developing a Clinical Trials Infrastructure in the United States

Clinical trials in the United States have a rich history of involving academic, industry, and government institutions (
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Transforming the Economics of Clinical Trials

Clinical trials are a means of gathering information about medical products or services. In medicine, however, they are also the fundament
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Trying to Practice What I Preached: Helping My Parents at the End of Their Lives

Once again, the challenge of how to constrain rising health care expenditures has caught the public inter
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Aligning Cultural and Financial Incentives for Clinical Trials

One session of the November 2011 Institute of Medicine (IOM) workshop Envisioning a Transformed Clinical Trials Enterpris
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Educating the Workforce for a Transformed Clinical Research Enterprise

Health care in America is in crisis. Population health and patient outcomes are deteriorating relative to the res
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Developing a Robust Clinical Trials Workforce

The gap between the growing demand for evidence to inform practice and our current state of knowledge calls for serious consideration abou
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Healing Humankind One Patient at a Time

Four years ago, UCLA’s medical center was ranked as an honor-roll hospital by U.S. News and World Report—but our patients would seldom “refer us
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